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Description* :

Understanding of screening techniques for bioactive molecules, and more generally in vitro tests used to measure a biological event in the perspective of drug discovery or diagnosis.

1) Pharmacological and biophysical fundamentals describing a biological event, target of biological tests:

2) Biological tests for the development of medicines or diagnostics

3) Applications, case studies, critical analyses.

Mots-clés : High throuput Screening, high content screening, fluorescence, binding, biological activity, In vitro bioassay

Objectifs* :

Be able to choose the biological screening and testing techniques suitable for the evaluation and optimisation of bioactive molecules.

Understand from a molecular point of view the technologies associated with diagnostic and screening tools and be able to design new chemical tools for this purpose.